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Kev Taw Qhia Txog Chav Kuaj Mob

Lub Chaw Kuaj Xyuas (lossis Lub Chaw Tswj Xyuas Qhov Zoo) hauv lub Hoobkas rho tawm cov nroj tsuag ua haujlwm ua "lub plawv" thiab "chav haujlwm txiav txim plaub ntug" ntawm lub chaw. Nws yog chav haujlwm tseem ceeb uas muaj lub luag haujlwm los xyuas kom meej tias cov khoom muaj kev nyab xeeb, kev ua haujlwm zoo, kev sib xws, thiab kev ua raws li txoj cai. Ua haujlwm ywj pheej ntawm lub chaw tsim khoom, nws ua haujlwm saib xyuas qhov zoo thiab lub hwj chim, muab kev txhawb nqa cov ntaub ntawv tshawb fawb thiab lub hom phiaj rau txhua kauj ruam txij li kev noj cov khoom siv raw mus txog rau kev tso tawm cov khoom tiav.

Cov chaw soj nstuam niaj hnub no feem ntau yog tsim raws li cov qauv xws li GMP (Kev Ua Haujlwm Zoo) thiab CNAS (Kev Pabcuam Kev Pom Zoo Hauv Tebchaws Suav rau Kev Ntsuam Xyuas Kev Ua Raws Cai). Lawv tau muab faib ua ntau qhov chaw ua haujlwm, xws li Chaw Kuaj Mob Physicochemical, Chaw Tshawb Fawb Cov Cuab Yeej, Chaw Kuaj Mob Microbiological, thiab Chaw Npaj Qauv & Khaws Cia. Lub chaw soj nstuam muaj ntau yam cuab yeej siv siab heev thiab muaj pab pawg kws tshaj lij uas muaj keeb kwm hauv chemistry, tshuaj, thiab biology. Nws lub luag haujlwm tseem ceeb suav nrog: kev txheeb xyuas thiab kev lees txais cov khoom siv raw, kev tswj hwm thaum lub sijhawm tsim khoom, kev sim ua tiav ntawm cov khoom tiav, kev tshawb fawb txog kev ruaj khov, thiab kev tsim kho thiab kev lees paub txoj kev.

txog-peb-3

Cov txiaj ntsig tseem ceeb

Cov hauv qab no yog cov khoom tseem ceeb uas tau ua rau cov khoom tiav lawm ntawm cov nroj tsuag, nrog rau cov lus piav qhia txog lawv cov yam ntxwv yooj yim.

Labrador (1)

Kev Ntsuas Kev Ua Haujlwm (Kev Ntsuas Cov Khoom Xyaw Nquag)

Qhov no yog qhov kev sim tseem ceeb kom ntseeg tau tias cov extract xa nws cov txiaj ntsig biological uas tau npaj tseg.
· Txoj Kev: Feem ntau yog High-Performance Liquid Chromatography (HPLC) thiab Gas Chromatography (GC).
· Piv txwv ntawm Cov Txheej Txheem Tseem Ceeb:
· Cuab Yeej Siv: HPLC system nruab nrog Diode Array Detector (DAD) lossis UV-Vis Detector.
· Kab: C18 kem rov qab-theem (cov lus qhia dav dav: 250 hli × 4.6 hli, 5 μm).
· Theem Txawb: Npaj raws li cov khoom ntawm lub hom phiaj, piv txwv li, methanol-dej lossis acetonitrile-dej systems, tej zaum nrog phosphoric lossis acetic acid rau kev kho pH.
· Tus Nqi Nqus: Feem ntau 0.8-1.2 ml / feeb.
Kub ntawm kem: Feem ntau tswj tau ntawm 30 - 40 ° C.
Kev Tshawb Pom Qhov Ntev: Teem raws li qhov siab tshaj plaws ntawm qhov nqus ntawm lub hom phiaj sib xyaw, piv txwv li, 280 nm rau EGCG hauv Green Tea Extract.
· Lub Hom Phiaj: Yuav kom ntseeg tau tias cov ntsiab lus ntawm cov cim tshuaj (piv txwv li, Ginsenosides, Pomegranate Ellagic Acid, Soy Isoflavones) ua tau raws li cov lus qhia (piv txwv li, ≥98% lossis cov qauv ntsuas xws li 40% -50%).

Labrador (2)

Kev Ntsuas Kev Nyab Xeeb

Cov kev ntsuam xyuas no yog qhov tseem ceeb rau kev siv cov khoom kawg kom muaj kev nyab xeeb.
Kev Ntsuas Hlau Hnyav:
· Txoj Kev: Atomic Absorption Spectrophotometry (AAS) lossis Inductively Coupled Plasma Mass Spectrometry (ICP-MS) raws li cov lus qhia pharmacopoeial (piv txwv li, Suav Pharmacopoeia General Tshooj 0821).
· Cov Txheej Txheem/Kev Txwv: Feem ntau yog kev ntsuam xyuas rau Lead (Pb), Cadmium (Cd), Arsenic (As), Mercury (Hg), thiab lwm yam. Cov kev txwv yog nruj heev; piv txwv li, Lead (Pb) ≤ 5 mg/kg, Cadmium (Cd) ≤ 0.5 mg/kg, nyob ntawm seb cov khoom siv thiab cov qauv ntawm cov neeg siv khoom.
Kev Ntsuas Cov Tshuaj Tua Kab Uas Muaj Tshuaj Tua Kab:
· Txoj Kev: Kev Siv Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS) thiab Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
· Cov Txheej Txheem: Tshuaj ntsuam xyuas ntau pua yam tshuaj tua kab uas seem. Cov kev txwv no ua raws li cov cai nruj xws li EU EC 396/2005, feem ntau ntawm ppb (qhov chaw ib billion).
Kev Ntsuas Txwv Kab Mob:
· Txoj Kev: Txoj kev suav phaj, txoj kev lim dej membrane.
· Cov Txheej Txheem/Kev Txwv:
Tag Nrho Cov Kab Mob Uas Muaj Aerobic Microbial: ≤ 1000 CFU/g
Tag Nrho Cov Poov Xab Thiab Cov Pwm Ua Ke: ≤ 100 CFU/g
· Escherichia coli: Tsis muaj nyob rau hauv 1g
Kab mob Salmonella: Tsis muaj nyob rau hauv 10g

Labrador (3)

Kev Ntsuas Lub Cev thiab Tshuaj Lom Zem Ib Txwm Muaj

Cov ntsuas no qhia txog cov khoom siv lub cev thiab tshuaj lom neeg yooj yim ntawm cov khoom.

Cov dej noo:
· Txoj Kev: Karl Fischer Titration (nyiam dua) lossis Poob thaum ziab.
· Cov Txheej Txheem/Kev Txwv: Feem ntau yuav tsum tau ≤ 5.0%, tej zaum yuav nruj dua rau cov khoom hygroscopic.
Cov ntsiab lus ntawm cov tshauv:
· Txoj Kev: Kev hlawv kub heev (Cua sov Muffle).
· Cov Txheej Txheem: Muaj xws li Cov Tshauv Tag Nrho thiab Cov Tshauv Uas Tsis Yaj Hauv Kua Txob, siv los tswj cov khoom tsis muaj kuab lom. Cov kev txwv sib txawv raws li qhov chaw cog qoob loo.
Cov Khoom seem ntawm cov kuab tshuaj:
· Txoj Kev: Headspace Gas Chromatography (HS-GC).
· Cov Txheej Txheem/Kev Txwv: Raws li ICH (International Council for Harmonisation) cov lus qhia, piv txwv li, qhov txwv rau Ethanol residue feem ntau yog 5000 ppm (0.5%).
· Kev Faib Qhov Loj ntawm Cov Khoom Me Me (rau cov khoom hmoov):
· Txoj Kev: Laser Particle Size Analyzer.
· Cov Txheej Txheem: D50, D90, thiab lwm yam, tswj hwm raws li tus neeg siv khoom xav tau, piv txwv li, 100% txog 80 mesh.

Labrador (4)

Lwm cov kev ntsuam xyuas siab heev

Chromatographic Fingerprint: Tsim kom muaj tus cwj pwm "chemical fingerprint" ntawm cov khoom siv HPLC lossis GC, siv rau kev tswj xyuas zoo tag nrho thiab kev ntsuam xyuas qhov sib xws ntawm cov tshuaj extracts nyuaj.

Hauv kev xaus lus, los ntawm cov khoom kuaj mob thiab kev tswj hwm nruj uas tau piav qhia saum toj no, lub chaw kuaj mob tsim kom muaj kev thaiv kev siv tshuab zoo. Qhov no ua kom ntseeg tau tias txhua pawg ntawm cov nroj tsuag extract yog qhov zoo heev, muaj kev nyab xeeb, txhim khu kev qha, thiab ua tau raws li cov kev cai nruj ntawm ob qho tib si thoob ntiaj teb thiab cov neeg siv khoom.